Business and Technology News

An opioid that Avenue Therapeutics reformulated for treating post-surgical pain in hospital settings has been rejected by the FDA due to safety concerns. The Avenue (NASDAQ: ATXI) drug is an intravenous formulation of tramadol, an opioid that first reached the US market 25 years ago in pill form. Now New York-based Avenue is trying to […]

The first generation of CRISPR-based therapies showed how the technology can edit DNA, making genetic fixes to unwanted mutations. But those treatments use the CRISPR system as scientists found it in nature, which means it still has limitations when applied to humans, says Benjamin Oakes, CEO of Scribe Therapeutics. Scribe aims to develop gene-editing therapies […]

Scientists at microbiome therapy developers often talk about the importance of community, how the bugs in our gut act in concert in addition to their individual roles. That’s important for microbiome health and for microbe-based therapies, says Emily Drabant Conley, CEO of startup Federation Bio. Conley’s company is developing therapies that build on the understanding of […]

[Updated 10/1/2020. See below.] Genfit is halting all work on its lead drug in the fatty liver disorder nonalcoholic steatohepatitis (NASH) and implementing a corporate restructuring that will cut 40 percent of its staff, splitting the remaining workforce into two distinct business units. The announcement after the market close on Wednesday follows the May failure […]

Section Page news and features from Crain's New York Business

Mayor Eric Adams’ call for housing is just the latest blow to the area, fashion manufacturers say

Investors appear excited about algorithms writing content 

Unmarried, working adults now pay more to rent a studio apartment than residents of any other U.S. city

From Hudson Yards to Willets Point, these are the leading contenders

Institutions are pulling out because they want to be judged on more wide-ranging criteria including student diversity and commitment to social justice

The move could hamstring the Chinese tech giant if it prevents the firm’s customers from getting the latest versions of services such as Maps and Gmail.

Shareholders are voting on whether to push the tech giant to examine the human rights and financial risks of the surveillance technology.

Artificial intelligence may help doctors make more accurate readings of CT scans used to screen for lung cancer.

The great hope for people without a bachelor’s degree hasn’t yet spread beyond small-scale success stories.

When it comes to disinformation, all signs suggest the 2020 presidential campaign will make 2016 look like a mere test run, our columnist writes.

The price was relatively small, but the deal may have a big impact on the race between the United States and China to build more powerful computers.